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doi: 10.3390/ijms18061221 185 XuHBaoXKongHYangJLiYSunZ

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To investigate whether a higher production titre of native product can be achieved in yeast based on non-genotypic cell-to-cell variation, here we used glutathione (GSH) as an exemplar product for the following reasons: (1) the commercial production of GSH is mainly in S

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Compared with control (i.e., + ) cells, 0 cells expressed mitochondrial genes at undetectable levels and were entirely deficient in oxidative metabolism, as detected using Seahorse technology (Fig S2C and D)